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Human embryonic stem cells have a unique epigenetic signature

Human embryonic stem (hES) cells originate during an embryonic period of active epigenetic remodeling. DNA methylation patterns are likely to be critical for their self-renewal and pluripotence. We compared the DNA methylation status of 1536 CpG sites (from 371 genes) in 14 independently isolated hE...

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Detalhes bibliográficos
Main Authors: Bibikova, Marina, Chudin, Eugene, Wu, Bonnie, Zhou, Lixin, Garcia, Eliza Wickham, Liu, Ying, Shin, Soojung, Plaia, Todd W., Auerbach, Jonathan M., Arking, Dan E., Gonzalez, Rodolfo, Crook, Jeremy, Davidson, Bruce, Schulz, Thomas C., Robins, Allan, Khanna, Aparna, Sartipy, Peter, Hyllner, Johan, Vanguri, Padmavathy, Savant-Bhonsale, Smita, Smith, Alan K., Chakravarti, Aravinda, Maitra, Anirban, Rao, Mahendra, Barker, David L., Loring, Jeanne F., Fan, Jian-Bing
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1557765/
https://ncbi.nlm.nih.gov/pubmed/16899657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.5319906
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