5-Hydroxymethylcytosine is associated with enhancers and gene bodies in human embryonic stem cells

BACKGROUND: 5-Hydroxymethylcytosine (5hmC) was recently found to be abundantly present in certain cell types, including embryonic stem cells. There is growing evidence that TET proteins, which convert 5-methylcytosine (5mC) to 5hmC, play important biological roles. To further understand the function...

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Bibliographic Details
Main Authors: Stroud, Hume, Feng, Suhua, Morey Kinney, Shannon, Pradhan, Sriharsa, Jacobsen, Steven E
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218842/
https://ncbi.nlm.nih.gov/pubmed/21689397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2011-12-6-r54
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