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A single dividing cell population with imbalanced fate drives oesophageal tumour growth

Understanding the cellular mechanisms of tumour growth is key for designing rational anti-cancer treatment. Here we used genetic lineage tracing to quantify cell behaviour during neoplastic transformation in a model of oesophageal carcinogenesis. We found that cell behaviour was convergent across pr...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Frede, Julia, Greulich, Philip, Nagy, Tibor, Simons, Benjamin D, Jones, Philip H
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870829/
https://ncbi.nlm.nih.gov/pubmed/27548914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3400
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