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Neutral competition of stem cells is skewed by proliferative changes downstream of Hh and Hpo

Neutral competition, an emerging feature of stem cell homeostasis, posits that individual stem cells can be lost and replaced by their neighbors stochastically, resulting in chance dominance of a clone at the niche. A single stem cell with an oncogenic mutation could bias this process and clonally s...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Amoyel, Marc, Simons, Benjamin D, Bach, Erika A
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253521/
https://ncbi.nlm.nih.gov/pubmed/25092766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201387500
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