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Defining the clonal dynamics leading to mouse skin tumour initiation

The changes that occur in cell dynamics following oncogenic mutation that lead to the development of tumours are currently unknown. Here, using skin epidermis as a model, we assessed the impact of oncogenic hedgehog signalling in distinct cell populations and their capacity to induce basal cell carc...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Sánchez-Danés, Adriana, Hannezo, Edouard, Larsimont, Jean-Christophe, Liagre, Mélanie, Youssef, Khalil Kass, Simons, Benjamin D, Blanpain, Cédric
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068560/
https://ncbi.nlm.nih.gov/pubmed/27459053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature19069
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