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Deep sequencing as a probe of normal stem cell fate and preneoplasia in human epidermis

Using deep sequencing technology, methods based on the sporadic acquisition of somatic DNA mutations in human tissues have been used to trace the clonal evolution of progenitor cells in diseased states. However, the potential of these approaches to explore cell fate behavior of normal tissues and th...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Autor principal: Simons, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711853/
https://ncbi.nlm.nih.gov/pubmed/26699486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516123113
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