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Deep sequencing as a probe of normal stem cell fate and preneoplasia in human epidermis

Using deep sequencing technology, methods based on the sporadic acquisition of somatic DNA mutations in human tissues have been used to trace the clonal evolution of progenitor cells in diseased states. However, the potential of these approaches to explore cell fate behavior of normal tissues and th...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autor: Simons, Benjamin D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4711853/
https://ncbi.nlm.nih.gov/pubmed/26699486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1516123113
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