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2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size

Variation in cerebral cortex size and complexity is thought to contribute to differences in cognitive ability between humans and other animals. Here we compare cortical progenitor cell output in humans and three nonhuman primates using directed differentiation of pluripotent stem cells (PSCs) in adh...

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Bibliografiske detaljer
Udgivet i:Cell Stem Cell
Main Authors: Otani, Tomoki, Marchetto, Maria C., Gage, Fred H., Simons, Benjamin D., Livesey, Frederick J.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826446/
https://ncbi.nlm.nih.gov/pubmed/27049876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.03.003
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