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2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size

Variation in cerebral cortex size and complexity is thought to contribute to differences in cognitive ability between humans and other animals. Here we compare cortical progenitor cell output in humans and three nonhuman primates using directed differentiation of pluripotent stem cells (PSCs) in adh...

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Detalhes bibliográficos
Publicado no:Cell Stem Cell
Main Authors: Otani, Tomoki, Marchetto, Maria C., Gage, Fred H., Simons, Benjamin D., Livesey, Frederick J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4826446/
https://ncbi.nlm.nih.gov/pubmed/27049876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.03.003
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