Chloroquine Resistance in Plasmodium falciparum Malaria Parasites Conferred by pfcrt Mutations

por Sidhu, Amar Bir Singh, Verdier-Pinard, Dominik, Fidock, David A.
Publicado em 2002

Decreasing pfmdr1 Copy Number in Plasmodium falciparum Malaria Heightens Susceptibility to Mefloquine, Lumefantrine, Halofantrine, Quinine, and Artemisinin

por Sidhu, Amar Bir Singh, Uhlemann, Anne-Catrin, Valderramos, Stephanie G., Valderramos, Juan-Carlos, Krishna, Sanjeev, Fidock, David A.
Publicado em 2006

Evidence for a Central Role for PfCRT in Conferring Plasmodium falciparum Resistance to Diverse Antimalarial Agents

por Johnson, David J., Fidock, David A., Mungthin, Mathirut, Lakshmanan, Viswanathan, Sidhu, Amar Bir Singh, Bray, Patrick G., Ward, Stephen A.
Publicado em 2004

Genetic linkage of pfmdr1 with food vacuolar solute import in Plasmodium falciparum

por Rohrbach, Petra, Sanchez, Cecilia P, Hayton, Karen, Friedrich, Oliver, Patel, Jigar, Sidhu, Amar Bir Singh, Ferdig, Michael T, Fidock, David A, Lanzer, Michael
Publicado em 2006

Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites§

por Hunt, Paul, Afonso, Ana, Creasey, Alison, Culleton, Richard, Sidhu, Amar Bir Singh, Logan, John, Valderramos, Stephanie G, McNae, Iain, Cheesman, Sandra, do Rosario, Virgilio, Carter, Richard, Fidock, David A, Cravo, Pedro
Publicado em 2007

In Vivo and In Vitro Antimalarial Properties of Azithromycin-Chloroquine Combinations That Include the Resistance Reversal Agent Amlodipine

por Pereira, Marcus R., Henrich, Philipp P., Sidhu, Amar bir Singh, Johnson, David, Hardink, Joel, Van Deusen, Jeffrey, Lin, Jian, Gore, Katrina, O'Brien, Connor, Wele, Mamadou, Djimde, Abdoulaye, Chandra, Richa, Fidock, David A.
Publicado em 2011

A critical role for PfCRT K76T in Plasmodium falciparum verapamil-reversible chloroquine resistance

por Lakshmanan, Viswanathan, Bray, Patrick G, Verdier-Pinard, Dominik, Johnson, David J, Horrocks, Paul, Muhle, Rebecca A, Alakpa, George E, Hughes, Ruth H, Ward, Steve A, Krogstad, Donald J, Sidhu, Amar Bir Singh, Fidock, David A
Publicado em 2005

Inferring Developmental Stage Composition from Gene Expression in Human Malaria

por Joice, Regina, Narasimhan, Vagheesh, Montgomery, Jacqui, Sidhu, Amar Bir, Oh, Keunyoung, Meyer, Evan, Pierre-Louis, Willythssa, Seydel, Karl, Milner, Danny, Williamson, Kim, Wiegand, Roger, Ndiaye, Daouda, Daily, Johanna, Wirth, Dyann, Taylor, Terrie, Huttenhower, Curtis, Marti, Matthias
Publicado em 2013

Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum

por Dharia, Neekesh V, Sidhu, Amar Bir Singh, Cassera, María Belén, Westenberger, Scott J, Bopp, Selina ER, Eastman, Rich T, Plouffe, David, Batalov, Serge, Park, Daniel J, Volkman, Sarah K, Wirth, Dyann F, Zhou, Yingyao, Fidock, David A, Winzeler, Elizabeth A
Publicado em 2009

Mutations in the P. falciparum Digestive Vacuole Transmembrane Protein PfCRT and Evidence for Their Role in Chloroquine Resistance

por Fidock, David A., Nomura, Takashi, Talley, Angela K., Cooper, Roland A., Dzekunov, Sergey M., Ferdig, Michael T., Ursos, Lyann M. B., Sidhu, Amar bir Singh, Naudé, Bronwen, Deitsch, Kirk W., Su, Xin-zhuan, Wootton, John C., Roepe, Paul D., Wellems, Thomas E.
Publicado em 2000

Optimization of Potent Inhibitors of P. falciparum Dihydroorotate Dehydrogenase for the Treatment of Malaria

por Skerlj, Renato T., Bastos, Cecilia M., Booker, Michael L., Kramer, Martin L., Barker, Robert H., Celatka, Cassandra A., O’Shea, Thomas J., Munoz, Benito, Sidhu, Amar Bir, Cortese, Joseph F., Wittlin, Sergio, Papastogiannidis, Petros, Angulo-Barturen, Inigo, Jimenez-Diaz, Maria Belen, Sybertz, Edmund
Publicado em 2011

The Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role In the Development of Liver Stage Malarial Parasites

por Yu, Min, Santha Kumar, T. R., Nkrumah, Louis J., Coppi, Alida, Retzlaff, Silke, Li, Celeste D., Kelly, Brendan J., Moura, Pedro A., Lakshmanan, Viswanathan, Freundlich, Joel S., Valderramos, Juan-Carlos, Vilcheze, Catherine, Siedner, Mark, Tsai, Jennifer H.-C., Falkard, Brie, Sidhu, Amar bir Singh, Purcell, Lisa A., Gratraud, Paul, Kremer, Laurent, Waters, Andy P., Schiehser, Guy, Jacobus, David P., Janse, Chris J., Ager, Arba, Jacobs, William R., Sacchettini, James C., Heussler, Volker, Sinnis, Photini, Fidock, David A.
Publicado em 2008

Novel Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase with Anti-malarial Activity in the Mouse Model

por Booker, Michael L., Bastos, Cecilia M., Kramer, Martin L., Barker, Robert H., Skerlj, Renato, Sidhu, Amar Bir, Deng, Xiaoyi, Celatka, Cassandra, Cortese, Joseph F., Guerrero Bravo, Jose E., Crespo Llado, Keila N., Serrano, Adelfa E., Angulo-Barturen, Iñigo, Jiménez-Díaz, María Belén, Viera, Sara, Garuti, Helen, Wittlin, Sergio, Papastogiannidis, Petros, Lin, Jing-wen, Janse, Chris J., Khan, Shahid M., Duraisingh, Manoj, Coleman, Bradley, Goldsmith, Elizabeth J., Phillips, Margaret A., Munoz, Benito, Wirth, Dyann F., Klinger, Jeffrey D., Wiegand, Roger, Sybertz, Edmund
Publicado em 2010

Aminoindoles, a Novel Scaffold with Potent Activity against Plasmodium falciparum

por Barker, Robert H., Urgaonkar, Sameer, Mazitschek, Ralph, Celatka, Cassandra, Skerlj, Renato, Cortese, Joseph F., Tyndall, Erin, Liu, Hanlan, Cromwell, Mandy, Sidhu, Amar Bir, Guerrero-Bravo, Jose E., Crespo-Llado, Keila N., Serrano, Adelfa E., Lin, Jing-wen, Janse, Chris J., Khan, Shahid M., Duraisingh, Manoj, Coleman, Bradley I., Angulo-Barturen, Inigo, Jiménez-Díaz, María Belén, Magán, Noemí, Gomez, Vanesa, Ferrer, Santiago, Martínez, María Santos, Wittlin, Sergio, Papastogiannidis, Petros, O'Shea, Thomas, Klinger, Jeffrey D., Bree, Mark, Lee, Edward, Levine, Mikaela, Wiegand, Roger C., Munoz, Benito, Wirth, Dyann F., Clardy, Jon, Bathurst, Ian, Sybertz, Edmund
Publicado em 2011