Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum

BACKGROUND: The identification of genetic changes that confer drug resistance or other phenotypic changes in pathogens can help optimize treatment strategies, support the development of new therapeutic agents, and provide information about the likely function of genes. Elucidating mechanisms of phen...

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Bibliografiske detaljer
Main Authors: Dharia, Neekesh V, Sidhu, Amar Bir Singh, Cassera, María Belén, Westenberger, Scott J, Bopp, Selina ER, Eastman, Rich T, Plouffe, David, Batalov, Serge, Park, Daniel J, Volkman, Sarah K, Wirth, Dyann F, Zhou, Yingyao, Fidock, David A, Winzeler, Elizabeth A
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2688282/
https://ncbi.nlm.nih.gov/pubmed/19216790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2009-10-2-r21
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