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Validation of isoleucine utilization targets in Plasmodium falciparum
Intraerythrocytic malaria parasites can obtain nearly their entire amino acid requirement by degrading host cell hemoglobin. The sole exception is isoleucine, which is not present in adult human hemoglobin and must be obtained exogenously. We evaluated two compounds for their potential to interfere...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3029723/ https://ncbi.nlm.nih.gov/pubmed/21205898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011560108 |
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