Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1

by Fer, Nicole D, Shoemaker, Robert H, Monks, Anne
Published 2010

Hypoxic induction of an HIF-1α–dependent bFGF autocrine loop drives angiogenesis in human endothelial cells

by Calvani, Maura, Rapisarda, Annamaria, Uranchimeg, Badarch, Shoemaker, Robert H., Melillo, Giovanni
Published 2006

Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress

by Aggarwal, Monika, Sommers, Joshua A., Shoemaker, Robert H., Brosh, Robert M.
Published 2011

Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression

by Lubet, Ronald A., Steele, Vernon E., Shoemaker, Robert H., Grubbs, Clinton J.
Published in Cancer Prev Res (Phila) (2018)

The NCI’s PREVENT Cancer Preclinical Drug Development Program: Overview, Current Projects, Animal Models, Agent Development Strategies, and Molecular Targets

by Shoemaker, Robert H., Suen, Chen S., Holmes, Cathy A., Fay, Judith R., Steele, Vernon E.
Published in Semin Oncol (2015)

Evaluation of the STAT3 inhibitor GLG-302 for the prevention of estrogen receptor-positive and -negative mammary cancers

by Shoemaker, Robert H., Fox, Jennifer T., Juliana, M. Margaret, Moeinpour, Fariba L., Grubbs, Clinton J.
Published in Oncol Rep (2019)

Data Mining of NCI’s Anticancer Screening Database Reveals Mitochondrial Complex I Inhibitors Cytotoxic to Leukemia Cell Lines

by Glover, Constance J., Rabow, Alfred A., Isgor, Yasemin G., Shoemaker, Robert H., Covell, David G.
Published 2006

Immunoprevention of KRAS-driven lung adenocarcinoma by a multipeptide vaccine

by Pan, Jing, Zhang, Qi, Sei, Shizuko, Shoemaker, Robert H., Lubet, Ronald A., Wang, Yian, You, Ming
Published in Oncotarget (2017)

Gene expression profiling of alveolar soft-part sarcoma (ASPS)

by Stockwin, Luke H, Vistica, David T, Kenney, Susan, Schrump, David S, Butcher, Donna O, Raffeld, Mark, Shoemaker, Robert H
Published 2009

Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor

by Lountos, George T, Tropea, Joseph E, Zhang, Di, Jobson, Andrew G, Pommier, Yves, Shoemaker, Robert H, Waugh, David S
Published 2009

WERNER SYNDROME HELICASE HAS A CRITICAL ROLE IN DNA DAMAGE RESPONSES IN THE ABSENCE OF A FUNCTIONAL FANCONI ANEMIA PATHWAY

by Aggarwal, Monika, Banerjee, Taraswi, Sommers, Joshua A., Iannascoli, Chiara, Pichierri, Pietro, Shoemaker, Robert H., Brosh, Robert M.
Published 2013

12 arylstibonic acids that inhibit the DNA binding of five B-ZIP dimers

by Rishi, Vikas, Oh, Won-Jun, Heyerdahl, Sarah L., Zhao, Jianfei, Scudiero, Dominic, Shoemaker, Robert H., Vinson, Charles
Published in J Struct Biol (2010)

Identification of polymerase and processivity inhibitors of vaccinia DNA synthesis using a stepwise screening approach

by Silverman, Janice Elaine Y., Ciustea, Mihai, Shudofsky, Abigail M. Druck, Bender, Florent, Shoemaker, Robert H., Ricciardi, Robert P.
Published 2008

Discovery and Preliminary SAR of Bisbenzylisoquinoline Alkaloids as Inducers of C/EBPα

by Klausmeyer, Paul, McCloud, Thomas G., Scudiero, Dominic A., Currens, Michael J., Cardellina, John H., Shoemaker, Robert H.
Published 2012

X-ray Structures of Checkpoint Kinase 2 in Complex with Inhibitors that Target its Gatekeeper-Dependent Hydrophobic Pocket

by Lountos, George T., Jobson, Andrew G., Tropea, Joseph E., Self, Christopher R., Zhang, Guangtao, Pommier, Yves, Shoemaker, Robert H., Waugh, David S.
Published 2011

Structural Characterization of Inhibitor Complexes with Checkpoint Kinase 2 (Chk2), a Drug Target for Cancer Therapy

by Lountos, George T., Jobson, Andrew G., Tropea, Joseph E., Self, Christopher R., Zhang, Guangtao, Pommier, Yves, Shoemaker, Robert H., Waugh, David S.
Published 2011

Use of Biomarker Modulation in Normal Mammary Epithelium as a Correlate for Efficacy of Chemopreventive Agents Against Chemically-Induced Cancers

by Lubet, Ronald A., Heckman-Stoddard, Brandy M., Fox, Jennifer T., Moeinpour, Fariba, Juliana, M. Margaret, Shoemaker, Robert H., Grubbs, Clinton J.
Published in Cancer Prev Res (Phila) (2019)

Potent Antiviral Activity of North-Methanocarbathymidine against Kaposi's Sarcoma-Associated Herpesvirus

by Zhu, Weimin, Burnette, Angela, Dorjsuren, Dorjbal, Roberts, Paula E., Huleihel, Mahmoud, Shoemaker, Robert H., Marquez, Victor E., Agbaria, Riad, Sei, Shizuko
Published 2005

Cysteine 81 Is Critical for the Interaction of S100A4 and Myosin-IIA

by Dulyaninova, Natalya G., Hite, Karen M., Zencheck, Wendy D., Scudiero, Dominic A., Almo, Steven C., Shoemaker, Robert H., Bresnick, Anne R.
Published 2011

Induction of Apoptosis in Human Cancer Cells by Candidaspongiolide, a Novel Sponge Polyketide

by Trisciuoglio, Daniela, Uranchimeg, Badarch, Cardellina, John H., Meragelman, Tamara L., Matsunaga, Shigeki, Fusetani, Nobuhiru, Del Bufalo, Donatella, Shoemaker, Robert H., Melillo, Giovanni
Published 2008