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Identification of polymerase and processivity inhibitors of vaccinia DNA synthesis using a stepwise screening approach

Nearly all DNA polymerases require processivity factors to ensure continuous incorporation of nucleotides. Processivity factors are specific for their cognate DNA polymerases. For this reason, the vaccinia DNA polymerase (E9) and the proteins associated with processivity (A20 and D4) are excellent t...

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Sonraí Bibleagrafaíochta
Main Authors: Silverman, Janice Elaine Y., Ciustea, Mihai, Shudofsky, Abigail M. Druck, Bender, Florent, Shoemaker, Robert H., Ricciardi, Robert P.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3155815/
https://ncbi.nlm.nih.gov/pubmed/18621425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2008.05.010
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