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Identification of Non-Nucleoside DNA Synthesis Inhibitors of Vaccinia Virus by High-Throughput Screening

Variola virus, the causative agent of smallpox, is a potential bio-weapon. The development of new antiviral compounds for smallpox prophylaxis and treatment is critical, especially since the virus can acquire resistance to the drugs that are currently available. We have identified novel small chemic...

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Detalhes bibliográficos
Main Authors: Ciustea, Mihai, Silverman, Janice Elaine Y., Shudofsky, Abigail M. Druck, Ricciardi, Robert P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650103/
https://ncbi.nlm.nih.gov/pubmed/18808105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800366g
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