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Cysteine 81 Is Critical for the Interaction of S100A4 and Myosin-IIA

[Image: see text] Overexpression of S100A4, a member of the S100 family of Ca(2+)-binding proteins, is associated with a number of human pathologies, including fibrosis, inflammatory disorders, and metastatic disease. The identification of small molecules that disrupt S100A4/target interactions prov...

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Detalhes bibliográficos
Main Authors: Dulyaninova, Natalya G., Hite, Karen M., Zencheck, Wendy D., Scudiero, Dominic A., Almo, Steven C., Shoemaker, Robert H., Bresnick, Anne R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220277/
https://ncbi.nlm.nih.gov/pubmed/21749055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200853y
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