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Use of Biomarker Modulation in Normal Mammary Epithelium as a Correlate for Efficacy of Chemopreventive Agents Against Chemically-Induced Cancers

In both estrogen receptor/progesterone receptor-positive (ER(+)/PR(+)) human breast cancer and in ER(+)/PR(+) cancers in the methylnitrosourea (MNU)-induced rat model, short-term modulation of proliferation in early cancers predicts preventive/therapeutic efficacy. We determined the effects of known...

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Detalhes bibliográficos
Publicado no:Cancer Prev Res (Phila)
Main Authors: Lubet, Ronald A., Heckman-Stoddard, Brandy M., Fox, Jennifer T., Moeinpour, Fariba, Juliana, M. Margaret, Shoemaker, Robert H., Grubbs, Clinton J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7060128/
https://ncbi.nlm.nih.gov/pubmed/31871222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-19-0318
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