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Discovery and Preliminary SAR of Bisbenzylisoquinoline Alkaloids as Inducers of C/EBPα

A high throughput in vitro screen has been developed to identify substances that induce expression of C/EBPα in tumor cells. An extract of the fruit of Gyrocarpus jacquinii showed induction of C/EBPα activity that was attributed by dereplication analysis to the presence of bisbenzylisoquinoline (BBI...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Klausmeyer, Paul, McCloud, Thomas G., Scudiero, Dominic A., Currens, Michael J., Cardellina, John H., Shoemaker, Robert H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3430122/
https://ncbi.nlm.nih.gov/pubmed/22766217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.06.017
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