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Discovery and Preliminary SAR of Bisbenzylisoquinoline Alkaloids as Inducers of C/EBPα
A high throughput in vitro screen has been developed to identify substances that induce expression of C/EBPα in tumor cells. An extract of the fruit of Gyrocarpus jacquinii showed induction of C/EBPα activity that was attributed by dereplication analysis to the presence of bisbenzylisoquinoline (BBI...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3430122/ https://ncbi.nlm.nih.gov/pubmed/22766217 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2012.06.017 |
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