Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1

Por Fer, Nicole D, Shoemaker, Robert H, Monks, Anne
Publicado em 2010

Hypoxic induction of an HIF-1α–dependent bFGF autocrine loop drives angiogenesis in human endothelial cells

Por Calvani, Maura, Rapisarda, Annamaria, Uranchimeg, Badarch, Shoemaker, Robert H., Melillo, Giovanni
Publicado em 2006

Inhibition of helicase activity by a small molecule impairs Werner syndrome helicase (WRN) function in the cellular response to DNA damage or replication stress

Por Aggarwal, Monika, Sommers, Joshua A., Shoemaker, Robert H., Brosh, Robert M.
Publicado em 2011

Screening of Chemopreventive Agents in Animal Models: Results on Reproducibility, Agents of a Given Class, and Agents Tested During Tumor Progression

Por Lubet, Ronald A., Steele, Vernon E., Shoemaker, Robert H., Grubbs, Clinton J.
Publicado no Cancer Prev Res (Phila) (2018)

The NCI’s PREVENT Cancer Preclinical Drug Development Program: Overview, Current Projects, Animal Models, Agent Development Strategies, and Molecular Targets

Por Shoemaker, Robert H., Suen, Chen S., Holmes, Cathy A., Fay, Judith R., Steele, Vernon E.
Publicado no Semin Oncol (2015)

Evaluation of the STAT3 inhibitor GLG-302 for the prevention of estrogen receptor-positive and -negative mammary cancers

Por Shoemaker, Robert H., Fox, Jennifer T., Juliana, M. Margaret, Moeinpour, Fariba L., Grubbs, Clinton J.
Publicado no Oncol Rep (2019)

Data Mining of NCI’s Anticancer Screening Database Reveals Mitochondrial Complex I Inhibitors Cytotoxic to Leukemia Cell Lines

Por Glover, Constance J., Rabow, Alfred A., Isgor, Yasemin G., Shoemaker, Robert H., Covell, David G.
Publicado em 2006

Immunoprevention of KRAS-driven lung adenocarcinoma by a multipeptide vaccine

Por Pan, Jing, Zhang, Qi, Sei, Shizuko, Shoemaker, Robert H., Lubet, Ronald A., Wang, Yian, You, Ming
Publicado no Oncotarget (2017)

Gene expression profiling of alveolar soft-part sarcoma (ASPS)

Por Stockwin, Luke H, Vistica, David T, Kenney, Susan, Schrump, David S, Butcher, Donna O, Raffeld, Mark, Shoemaker, Robert H
Publicado em 2009

Crystal structure of checkpoint kinase 2 in complex with NSC 109555, a potent and selective inhibitor

Por Lountos, George T, Tropea, Joseph E, Zhang, Di, Jobson, Andrew G, Pommier, Yves, Shoemaker, Robert H, Waugh, David S
Publicado em 2009

WERNER SYNDROME HELICASE HAS A CRITICAL ROLE IN DNA DAMAGE RESPONSES IN THE ABSENCE OF A FUNCTIONAL FANCONI ANEMIA PATHWAY

Por Aggarwal, Monika, Banerjee, Taraswi, Sommers, Joshua A., Iannascoli, Chiara, Pichierri, Pietro, Shoemaker, Robert H., Brosh, Robert M.
Publicado em 2013

12 arylstibonic acids that inhibit the DNA binding of five B-ZIP dimers

Por Rishi, Vikas, Oh, Won-Jun, Heyerdahl, Sarah L., Zhao, Jianfei, Scudiero, Dominic, Shoemaker, Robert H., Vinson, Charles
Publicado no J Struct Biol (2010)

Identification of polymerase and processivity inhibitors of vaccinia DNA synthesis using a stepwise screening approach

Por Silverman, Janice Elaine Y., Ciustea, Mihai, Shudofsky, Abigail M. Druck, Bender, Florent, Shoemaker, Robert H., Ricciardi, Robert P.
Publicado em 2008

Discovery and Preliminary SAR of Bisbenzylisoquinoline Alkaloids as Inducers of C/EBPα

Por Klausmeyer, Paul, McCloud, Thomas G., Scudiero, Dominic A., Currens, Michael J., Cardellina, John H., Shoemaker, Robert H.
Publicado em 2012

X-ray Structures of Checkpoint Kinase 2 in Complex with Inhibitors that Target its Gatekeeper-Dependent Hydrophobic Pocket

Por Lountos, George T., Jobson, Andrew G., Tropea, Joseph E., Self, Christopher R., Zhang, Guangtao, Pommier, Yves, Shoemaker, Robert H., Waugh, David S.
Publicado em 2011

Structural Characterization of Inhibitor Complexes with Checkpoint Kinase 2 (Chk2), a Drug Target for Cancer Therapy

Por Lountos, George T., Jobson, Andrew G., Tropea, Joseph E., Self, Christopher R., Zhang, Guangtao, Pommier, Yves, Shoemaker, Robert H., Waugh, David S.
Publicado em 2011

Use of Biomarker Modulation in Normal Mammary Epithelium as a Correlate for Efficacy of Chemopreventive Agents Against Chemically-Induced Cancers

Por Lubet, Ronald A., Heckman-Stoddard, Brandy M., Fox, Jennifer T., Moeinpour, Fariba, Juliana, M. Margaret, Shoemaker, Robert H., Grubbs, Clinton J.
Publicado no Cancer Prev Res (Phila) (2019)

Potent Antiviral Activity of North-Methanocarbathymidine against Kaposi's Sarcoma-Associated Herpesvirus

Por Zhu, Weimin, Burnette, Angela, Dorjsuren, Dorjbal, Roberts, Paula E., Huleihel, Mahmoud, Shoemaker, Robert H., Marquez, Victor E., Agbaria, Riad, Sei, Shizuko
Publicado em 2005

Cysteine 81 Is Critical for the Interaction of S100A4 and Myosin-IIA

Por Dulyaninova, Natalya G., Hite, Karen M., Zencheck, Wendy D., Scudiero, Dominic A., Almo, Steven C., Shoemaker, Robert H., Bresnick, Anne R.
Publicado em 2011

Induction of Apoptosis in Human Cancer Cells by Candidaspongiolide, a Novel Sponge Polyketide

Por Trisciuoglio, Daniela, Uranchimeg, Badarch, Cardellina, John H., Meragelman, Tamara L., Matsunaga, Shigeki, Fusetani, Nobuhiru, Del Bufalo, Donatella, Shoemaker, Robert H., Melillo, Giovanni
Publicado em 2008