Signaling pathways and immune evasion mechanisms in classical Hodgkin lymphoma

по Liu, W. Robert, Shipp, Margaret A.
Опубликовано в: Blood (2017)

Signaling pathways and immune evasion mechanisms in classical Hodgkin lymphoma

по Liu, W. Robert, Shipp, Margaret A.
Опубликовано в: Hematology Am Soc Hematol Educ Program (2017)

BAL1 and BBAP Are Regulated by a Gamma Interferon-Responsive Bidirectional Promoter and Are Overexpressed in Diffuse Large B-Cell Lymphomas with a Prominent Inflammatory Infiltrate

по Juszczynski, Przemyslaw, Kutok, Jeffery L., Li, Cheng, Mitra, Joydeep, Aguiar, Ricardo C. T., Shipp, Margaret A.
Опубликовано 2006

BAL1 and Its Partner E3 Ligase, BBAP, Link Poly(ADP-Ribose) Activation, Ubiquitylation, and Double-Strand DNA Repair Independent of ATM, MDC1, and RNF8

по Yan, Qingsheng, Xu, Rong, Zhu, Liya, Cheng, Xin, Wang, Zhe, Manis, John, Shipp, Margaret A.
Опубликовано 2013

Selective JAK2 Inhibition Specifically Decreases Hodgkin Lymphoma and Mediastinal Large B-cell Lymphoma Growth In Vitro and In Vivo

по Hao, Yansheng, Chapuy, Bjoern, Monti, Stefano, Sun, Heather H., Rodig, Scott J., Shipp, Margaret A.
Опубликовано 2014

BBAP Monoubiquitylates Histone H4 at Lysine 91 and Selectively Modulates the DNA Damage Response

по Yan, Qingsheng, Dutt, Shilpee, Xu, Rong, Graves, Katherine, Juszczynski, Przemyslaw, Manis, John P., Shipp, Margaret A.
Опубликовано 2009

Heat Shock Protein 90 is a Rational Therapeutic Target in Diffuse Large B-cell Lymphoma

по Abramson, Jeremy S., Chen, Wen, Takahashi, Hidenobu, Juszczynski, Przemyslaw, Takeyama, Kunihiko, Kutok, Jeffery L., Shipp, Margaret A.
Опубликовано 2008

Transcriptional signature with differential expression of BCL6 target genes accurately identifies BCL6-dependent diffuse large B cell lymphomas

по Polo, Jose M., Juszczynski, Przemyslaw, Monti, Stefano, Cerchietti, Leandro, Ye, Kenny, Greally, John M., Shipp, Margaret, Melnick, Ari
Опубликовано 2007

Constitutive AP-1 Activity and EBV Infection Induce PD-L1 in Hodgkin Lymphomas and Post-transplant Lymphoproliferative Disorders: Implications for Targeted Therapy

по Green, Michael R., Rodig, Scott, Juszczynski, Przemyslaw, Ouyang, Jing, Sinha, Papiya, O’Donnell, Evan, Neuberg, Donna, Shipp, Margaret A.
Опубликовано 2012

BCL6 modulates tonic BCR signaling in diffuse large B-cell lymphomas by repressing the SYK phosphatase, PTPROt

по Juszczynski, Przemyslaw, Chen, Linfeng, O'Donnell, Evan, Polo, Jose M., Ranuncolo, Stella M., Dalla-Favera, Riccardo, Melnick, Ari, Shipp, Margaret A.
Опубликовано 2009

SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma

по Chen, Linfeng, Monti, Stefano, Juszczynski, Przemyslaw, Daley, John, Chen, Wen, Witzig, Thomas E., Habermann, Thomas M., Kutok, Jeffery L., Shipp, Margaret A.
Опубликовано 2008

No Evidence for the JAK2 (V617F) or JAK2 Exon 12 Mutations in Primary Mediastinal Large B-Cell Lymphoma

по Wu, David, Dutra, Bethany, Lindeman, Neal, Takahashi, Hidenobu, Takeyama, Kunihiko, Harris, Nancy L., Pinkus, Geraldine S., Longtine, Janina, Shipp, Margaret, Kutok, Jeffery L.
Опубликовано 2009

Expression of Programmed Cell Death 1 Ligand 2 (PD-L2) is a Distinguishing Feature of Primary Mediastinal (Thymic) Large B-cell Lymphoma and Associated with PDCD1LG2 Copy Gain

по Shi, Min, Roemer, Margaretha GM, Chapuy, Bjoern, Liao, Xiaoyun, Sun, Heather, Pinkus, Geraldine S., Shipp, Margaret A., Freeman, Gordon J., Rodig, Scott J.
Опубликовано в: Am J Surg Pathol (2014)

FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas

по Duan, Shanshan, Cermak, Lukas, Pagan, Julia K., Rossi, Mario, Martinengo, Cinzia, di Celle, Paola Francia, Chapuy, Bjoern, Shipp, Margaret, Chiarle, Roberto, Pagano, Michele
Опубликовано 2012

NLRC5/MHC class I transactivator is a target for immune evasion in cancer

по Yoshihama, Sayuri, Roszik, Jason, Downs, Isaac, Meissner, Torsten B., Vijayan, Saptha, Chapuy, Bjoern, Sidiq, Tabasum, Shipp, Margaret A., Lizee, Gregory A., Kobayashi, Koichi S.
Опубликовано в: Proc Natl Acad Sci U S A (2016)

The microenvironmental niche in classic Hodgkin lymphoma is enriched for CTLA-4–positive T cells that are PD-1–negative

по Patel, Sanjay S., Weirather, Jason L., Lipschitz, Mikel, Lako, Ana, Chen, Pei-Hsuan, Griffin, Gabriel K., Armand, Philippe, Shipp, Margaret A., Rodig, Scott J.
Опубликовано в: Blood (2019)

The AP1-dependent secretion of galectin-1 by Reed–Sternberg cells fosters immune privilege in classical Hodgkin lymphoma

по Juszczynski, Przemyslaw, Ouyang, Jing, Monti, Stefano, Rodig, Scott J., Takeyama, Kunihiko, Abramson, Jeremy, Chen, Wen, Kutok, Jeffery L., Rabinovich, Gabriel A., Shipp, Margaret A.
Опубликовано 2007

Aberrant expression of the dendritic cell marker TNFAIP2 by the malignant cells of Hodgkin lymphoma and primary mediastinal large B cell lymphoma distinguishes these tumor types fr...

по Kondratiev, Svetlana, Duraisamy, Sekhar, Unitt, Christine L., Green, Michael R., Pinkus, Geraldine, Shipp, Margaret A., Kutok, Jeffery L., Drapkin, Ronny I., Rodig, Scott J.
Опубликовано 2011

Immunohistochemical Detection of MYC-driven Diffuse Large B-Cell Lymphomas

по Kluk, Michael J., Chapuy, Bjoern, Sinha, Papiya, Roy, Alyssa, Cin, Paola Dal, Neuberg, Donna S., Monti, Stefano, Pinkus, Geraldine S., Shipp, Margaret A., Rodig, Scott J.
Опубликовано 2012

An open-label, multicohort Phase Ib trial of pembrolizumab (MK-3475) for advanced hematologic malignancies: KEYNOTE-013

по Ribrag, Vincent, Armand, Phillippe, Kuruvilla, John, Michot, Jean-Marie, Moskowitz, Craig H, Marinello, Patricia, Snyder, Ellen, Balakumaran, Arun, Shipp, Margaret A, Zinzani, Pier Luigi
Опубликовано в: J Immunother Cancer (2015)