NLRC5/MHC class I transactivator is a target for immune evasion in cancer

Cancer cells develop under immune surveillance, thus necessitating immune escape for successful growth. Loss of MHC class I expression provides a key immune evasion strategy in many cancers, although the molecular mechanisms remain elusive. MHC class I transactivator (CITA), known as “NLRC5” [NOD-li...

Full description

Saved in:
Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Yoshihama, Sayuri, Roszik, Jason, Downs, Isaac, Meissner, Torsten B., Vijayan, Saptha, Chapuy, Bjoern, Sidiq, Tabasum, Shipp, Margaret A., Lizee, Gregory A., Kobayashi, Koichi S.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889388/
https://ncbi.nlm.nih.gov/pubmed/27162338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602069113
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items