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NLRC5/CITA: a key player in cancer immune surveillance
Cancer cells need to escape immune surveillance for successful tumor growth. Loss of MHC class I has been described as a major immune evasion strategy in many cancers. MHC class I transactivator (CITA), NLRC5, has found to be a key transcription coactivator of MHC class I genes. Recent genetic studi...
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| Published in: | Trends Cancer |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5518632/ https://ncbi.nlm.nih.gov/pubmed/28718425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.trecan.2016.12.003 |
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