Heat Shock Protein 90 is a Rational Therapeutic Target in Diffuse Large B-cell Lymphoma

PURPOSE: Heat Shock Protein 90 (HSP90) is a molecular chaperone which stabilizes critical client proteins in multiple cancers. Herein, we assess the role of HSP90 and likely client proteins in the pathogenesis of diffuse large B-cell lymphoma (DLBCL), and evaluate the activity of HSP90 inhibitors in...

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Main Authors: Abramson, Jeremy S., Chen, Wen, Takahashi, Hidenobu, Juszczynski, Przemyslaw, Takeyama, Kunihiko, Kutok, Jeffery L., Shipp, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4029164/
https://ncbi.nlm.nih.gov/pubmed/19036086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2008.07484.x
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