The AP1-dependent secretion of galectin-1 by Reed–Sternberg cells fosters immune privilege in classical Hodgkin lymphoma

Classical Hodgkin lymphomas (cHLs) contain small numbers of neoplastic Reed–Sternberg (RS) cells within an extensive inflammatory infiltrate that includes abundant T helper (Th)-2 and T regulatory (T(reg)) cells. The skewed nature of the T cell infiltrate and the lack of an effective host antitumor...

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Main Authors: Juszczynski, Przemyslaw, Ouyang, Jing, Monti, Stefano, Rodig, Scott J., Takeyama, Kunihiko, Abramson, Jeremy, Chen, Wen, Kutok, Jeffery L., Rabinovich, Gabriel A., Shipp, Margaret A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2007
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1936978/
https://ncbi.nlm.nih.gov/pubmed/17670934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706017104
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