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Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma

Classical Hodgkin lymphoma (cHL) and mediastinal large B-cell lymphoma (MLBCL) are lymphoid malignancies with certain shared clinical, histologic, and molecular features. Primary cHLs and MLBCLs include variable numbers of malignant cells within an inflammatory infiltrate, suggesting that these tumo...

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Autors principals: Green, Michael R., Monti, Stefano, Rodig, Scott J., Juszczynski, Przemyslaw, Currie, Treeve, O'Donnell, Evan, Chapuy, Bjoern, Takeyama, Kunihiko, Neuberg, Donna, Golub, Todd R., Kutok, Jeffery L., Shipp, Margaret A.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995356/
https://ncbi.nlm.nih.gov/pubmed/20628145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-282780
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