Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma

Classical Hodgkin lymphoma (cHL) and mediastinal large B-cell lymphoma (MLBCL) are lymphoid malignancies with certain shared clinical, histologic, and molecular features. Primary cHLs and MLBCLs include variable numbers of malignant cells within an inflammatory infiltrate, suggesting that these tumo...

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Detalhes bibliográficos
Main Authors: Green, Michael R., Monti, Stefano, Rodig, Scott J., Juszczynski, Przemyslaw, Currie, Treeve, O'Donnell, Evan, Chapuy, Bjoern, Takeyama, Kunihiko, Neuberg, Donna, Golub, Todd R., Kutok, Jeffery L., Shipp, Margaret A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995356/
https://ncbi.nlm.nih.gov/pubmed/20628145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-282780
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