Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma

Classical Hodgkin lymphoma (cHL) and mediastinal large B-cell lymphoma (MLBCL) are lymphoid malignancies with certain shared clinical, histologic, and molecular features. Primary cHLs and MLBCLs include variable numbers of malignant cells within an inflammatory infiltrate, suggesting that these tumo...

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Bibliografische gegevens
Hoofdauteurs: Green, Michael R., Monti, Stefano, Rodig, Scott J., Juszczynski, Przemyslaw, Currie, Treeve, O'Donnell, Evan, Chapuy, Bjoern, Takeyama, Kunihiko, Neuberg, Donna, Golub, Todd R., Kutok, Jeffery L., Shipp, Margaret A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2010
Onderwerpen:
Lymphoid Neoplasia
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2995356/
https://ncbi.nlm.nih.gov/pubmed/20628145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-05-282780
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