Integrative Analysis Reveals an Outcome-associated and Targetable Pattern of p53 and Cell Cycle Deregulation in Diffuse Large B-cell Lymphoma

Diffuse large B-cell lymphoma (DLBCL) is a clinically and biologically heterogeneous disease with a high proliferation rate. By integrating copy number data with transcriptional profiles and performing pathway analysis in primary DLBCLs, we identified a comprehensive set of copy number alterations (...

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Bibliografiske detaljer
Main Authors: Monti, Stefano, Chapuy, Bjoern, Takeyama, Kunihiko, Rodig, Scott J, Hao, Yangsheng, Yeda, Kelly T., Inguilizian, Haig, Mermel, Craig, Curie, Treeve, Dogan, Ahmed, Kutok, Jeffery L, Beroukim, Rameen, Neuberg, Donna, Habermann, Thomas, Getz, Gad, Kung, Andrew L, Golub, Todd R, Shipp, Margaret A
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778921/
https://ncbi.nlm.nih.gov/pubmed/22975378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.07.014
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