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FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas
BCL6 is the product of a proto-oncogene implicated in the pathogenesis of human B-cell lymphomas(1,2). By binding specific DNA sequences, BCL6 controls the transcription of a variety of genes involved in B-cell development, differentiation and activation. BCL6 is overexpressed in the majority of pat...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3344385/ https://ncbi.nlm.nih.gov/pubmed/22113614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10688 |
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