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The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73
The transcription factor p73, a member of the p53 family, mediates cell-cycle arrest and apoptosis in response to DNA damage-induced cellular stress, acting thus as a proapoptotic gene. Similar to p53, p73 activity is regulated by post-translational modification, including phosphorylation, acetylati...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3865854/ https://ncbi.nlm.nih.gov/pubmed/19581926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.177 |
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