FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas

BCL6 is the product of a proto-oncogene implicated in the pathogenesis of human B-cell lymphomas(1,2). By binding specific DNA sequences, BCL6 controls the transcription of a variety of genes involved in B-cell development, differentiation and activation. BCL6 is overexpressed in the majority of pat...

Full description

Saved in:
Bibliographic Details
Main Authors: Duan, Shanshan, Cermak, Lukas, Pagan, Julia K., Rossi, Mario, Martinengo, Cinzia, di Celle, Paola Francia, Chapuy, Bjoern, Shipp, Margaret, Chiarle, Roberto, Pagano, Michele
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344385/
https://ncbi.nlm.nih.gov/pubmed/22113614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10688
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items