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NPM-ALK oncogenic tyrosine kinase controls T cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells

Transformed cells in lymphomas usually maintain the phenotype of the postulated normal lymphocyte from which they arise. By contrast, Anaplastic Large Cell Lymphoma (ALCL) is a T cell lymphoma with aberrant phenotype because of the defective expression of the T-cell receptor (TCR) and other T-cell s...

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書誌詳細
主要な著者: Ambrogio, Chiara, Martinengo, Cinzia, Voena, Claudia, Tondat, Fabrizio, Riera, Ludovica, di Celle, Paola Francia, Inghirami, Giorgio, Chiarle, Roberto
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784121/
https://ncbi.nlm.nih.gov/pubmed/19887607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2655
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