The Role of Oncogenic Tyrosine Kinase NPM-ALK in Genomic Instability

Genomic stability is crucial for cell life and transmitting genetic material is one of the primary tasks of the cell. The cell needs to be able to recognize any possible error and quickly repair it, and thus, cells have developed several mechanisms to detect DNA damage and promote repair during evol...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Cosimo Lobello, Vasilis Bikos, Andrea Janikova, Sarka Pospisilova
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI AG 2018-03-01
श्रृंखला:Cancers
विषय:
NPM-ALK (nucleophosmin-anaplastic lymphoma kinase)
ALK
anaplastic large cell lymphoma (ALCL)
DNA damage response
genomic instability
DNA repair
p53
MutS protein homolog 2 (MSH2)
ऑनलाइन पहुंच:http://www.mdpi.com/2072-6694/10/3/64
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