NPM-ALK oncogenic tyrosine kinase controls T cell identity by transcriptional regulation and epigenetic silencing in lymphoma cells

Transformed cells in lymphomas usually maintain the phenotype of the postulated normal lymphocyte from which they arise. By contrast, Anaplastic Large Cell Lymphoma (ALCL) is a T cell lymphoma with aberrant phenotype because of the defective expression of the T-cell receptor (TCR) and other T-cell s...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ambrogio, Chiara, Martinengo, Cinzia, Voena, Claudia, Tondat, Fabrizio, Riera, Ludovica, di Celle, Paola Francia, Inghirami, Giorgio, Chiarle, Roberto
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2009
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2784121/
https://ncbi.nlm.nih.gov/pubmed/19887607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2655
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