Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice

av Sgobio, Carmelo, Sun, Lixin, Ding, Jinhui, Herms, Jochen, Lovinger, David M., Cai, Huaibin
I publikationen Sci Rep (2019)

Optogenetic Measurement of Presynaptic Calcium Transients Using Conditional Genetically Encoded Calcium Indicator Expression in Dopaminergic Neurons

av Sgobio, Carmelo, Kupferschmidt, David A., Cui, Guohong, Sun, Lixin, Li, Zheng, Cai, Huaibin, Lovinger, David M.
Publicerad 2014

Enriched environment promotes behavioral and morphological recovery in a mouse model for the fragile X syndrome

av Restivo, Leonardo, Ferrari, Francesca, Passino, Enrica, Sgobio, Carmelo, Bock, Jörg, Oostra, Ben A., Bagni, Claudia, Ammassari-Teule, Martine
Publicerad 2005

Dopamine-Dependent Long-Term Depression Is Expressed in Striatal Spiny Neurons of Both Direct and Indirect Pathways: Implications for Parkinson's Disease

av Bagetta, Vincenza, Picconi, Barbara, Marinucci, Silvia, Sgobio, Carmelo, Pendolino, Valentina, Ghiglieri, Veronica, Fusco, Francesca R., Giampà, Carmen, Calabresi, Paolo
I publikationen J Neurosci (2011)

Tau deletion reduces plaque‐associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease

av Peters, Finn, Salihoglu, Hazal, Pratsch, Katrin, Herzog, Etienne, Pigoni, Martina, Sgobio, Carmelo, Lichtenthaler, Stefan F, Neumann, Ulf, Herms, Jochen
I publikationen EMBO J (2019)

Aldehyde dehydrogenase 1–positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum

av Sgobio, Carmelo, Wu, Junbing, Zheng, Wang, Chen, Xi, Pan, Jing, Salinas, Armando G., Davis, Margaret I., Lovinger, David M., Cai, Huaibin
I publikationen Sci Rep (2017)

No apparent transmission of transgenic α–synuclein into nigrostriatal dopaminergic neurons in multiple mouse models

av Sastry, Namratha, Zheng, Wang, Liu, Guoxiang, Wang, Helen, Chen, Xi, Cai, Michael, Contractor, Parth, Sgobio, Carmelo, Sun, Lixin, Xie, Chengsong, Cai, Huaibin
I publikationen Transl Neurodegener (2015)

Rebalance of Striatal NMDA/AMPA Receptor Ratio Underlies the Reduced Emergence of Dyskinesia During D2-Like Dopamine Agonist Treatment in Experimental Parkinson's Disease

av Bagetta, Vincenza, Sgobio, Carmelo, Pendolino, Valentina, Del Papa, Giulia, Tozzi, Alessandro, Ghiglieri, Veronica, Giampà, Carmela, Zianni, Elisa, Gardoni, Fabrizio, Calabresi, Paolo, Picconi, Barbara
I publikationen J Neurosci (2012)

LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

av Parisiadou, Loukia, Yu, Jia, Sgobio, Carmelo, Xie, Chengsong, Liu, Guoxiang, Sun, Lixin, Gu, Xing-Long, Lin, Xian, Crowley, Nicole A., Lovinger, David, Cai, Huaibin
Publicerad 2014

Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D‐serine homeostasis

av Zou, Chengyu, Crux, Sophie, Marinesco, Stephane, Montagna, Elena, Sgobio, Carmelo, Shi, Yuan, Shi, Song, Zhu, Kaichuan, Dorostkar, Mario M, Müller, Ulrike C, Herms, Jochen
I publikationen EMBO J (2016)

TrkB/BDNF-Dependent Striatal Plasticity and Behavior in a Genetic Model of Epilepsy: Modulation by Valproic Acid

av Ghiglieri, Veronica, Sgobio, Carmelo, Patassini, Stefano, Bagetta, Vincenza, Fejtova, Anna, Giampà, Carmela, Marinucci, Silvia, Heyden, Alexandra, Gundelfinger, Eckart D, Fusco, Francesca R, Calabresi, Paolo, Picconi, Barbara
Publicerad 2010

α-Synuclein Mutation Inhibits Endocytosis at Mammalian Central Nerve Terminals

av Xu, Jianhua, Wu, Xin-Sheng, Sheng, Jiansong, Zhang, Zhen, Yue, Hai-Yuan, Sun, Lixin, Sgobio, Carmelo, Lin, Xian, Peng, Shiyong, Jin, Yinghui, Gan, Lin, Cai, Huaibin, Wu, Ling-Gang
I publikationen J Neurosci (2016)

Distinct Levels of Dopamine Denervation Differentially Alter Striatal Synaptic Plasticity and NMDA Receptor Subunit Composition

av Paillé, Vincent, Picconi, Barbara, Bagetta, Vincenza, Ghiglieri, Veronica, Sgobio, Carmelo, Di Filippo, Massimiliano, Viscomi, Maria T., Giampà, Carmela, Fusco, Francesca R., Gardoni, Fabrizio, Bernardi, Giorgio, Greengard, Paul, Di Luca, Monica, Calabresi, Paolo
I publikationen J Neurosci (2010)

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic...

av Liu, Guoxiang, Sgobio, Carmelo, Gu, Xinglong, Sun, Lixin, Lin, Xian, Yu, Jia, Parisiadou, Loukia, Xie, Chengsong, Sastry, Namratha, Ding, Jinhui, Lohr, Kelly M., Miller, Gary W., Mateo, Yolanda, Lovinger, David M., Cai, Huaibin
I publikationen Hum Mol Genet (2015)

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease

av Dunn, Amy R., Stout, Kristen A., Ozawa, Minagi, Lohr, Kelly M., Hoffman, Carlie A., Bernstein, Alison I., Li, Yingjie, Wang, Minzheng, Sgobio, Carmelo, Sastry, Namratha, Cai, Huaibin, Caudle, W. Michael, Miller, Gary W.
I publikationen Proc Natl Acad Sci U S A (2017)

Conditional Expression of Parkinson's Disease-Related Mutant α-Synuclein in the Midbrain Dopaminergic Neurons Causes Progressive Neurodegeneration and Degradation of Transcription...

av Lin, Xian, Parisiadou, Loukia, Sgobio, Carmelo, Liu, Guoxiang, Yu, Jia, Sun, Lixin, Shim, Hoon, Gu, Xing-Long, Luo, Jing, Long, Cai-Xia, Ding, Jinhui, Mateo, Yolanda, Sullivan, Patricia H., Wu, Ling-Gang, Goldstein, David S., Lovinger, David, Cai, Huaibin
Publicerad 2012

Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second-Generation Amyloid-β Mouse Model

av Sacher, Christian, Blume, Tanja, Beyer, Leonie, Peters, Finn, Eckenweber, Florian, Sgobio, Carmelo, Deussing, Maximilian, Albert, Nathalie L., Unterrainer, Marcus, Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Brzak, Irena, Neumann, Ulf, Saito, Takashi, Saido, Takaomi C., Bartenstein, Peter, Rominger, Axel, Herms, Jochen, Brendel, Matthias
I publikationen J Nucl Med (2019)