No apparent transmission of transgenic α–synuclein into nigrostriatal dopaminergic neurons in multiple mouse models

BACKGROUND: α–synuclein (α–syn) is the main component of intracytoplasmic inclusions deposited in the brains of patients with Parkinson’s disease (PD) and certain other neurodegenerative disorders. Recent studies have explored the ability of α–syn to propagate between or across neighboring neurons a...

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Detalhes bibliográficos
Publicado no:Transl Neurodegener
Main Authors: Sastry, Namratha, Zheng, Wang, Liu, Guoxiang, Wang, Helen, Chen, Xi, Cai, Michael, Contractor, Parth, Sgobio, Carmelo, Sun, Lixin, Xie, Chengsong, Cai, Huaibin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4668690/
https://ncbi.nlm.nih.gov/pubmed/26635953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40035-015-0046-9
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