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Aldehyde dehydrogenase 1 defines and protects a nigrostriatal dopaminergic neuron subpopulation

Subpopulations of dopaminergic (DA) neurons within the substantia nigra pars compacta (SNpc) display a differential vulnerability to loss in Parkinson’s disease (PD); however, it is not clear why these subsets are preferentially selected in PD-associated neurodegeneration. In rodent SNpc, DA neurons...

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Detalhes bibliográficos
Main Authors: Liu, Guoxiang, Yu, Jia, Ding, Jinhui, Xie, Chengsong, Sun, Lixin, Rudenko, Iakov, Zheng, Wang, Sastry, Namratha, Luo, Jing, Rudow, Gay, Troncoso, Juan C., Cai, Huaibin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4071380/
https://ncbi.nlm.nih.gov/pubmed/24865427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72176
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