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Aldehyde dehydrogenase 1–positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum

Aldehyde dehydrogenase 1 (ALDH1A1)–positive dopaminergic (DA) neurons at the ventral substantia nigra pars compacta (SNpc) preferentially degenerate in Parkinson’s disease (PD). Their projection pattern and dopamine release properties, however, remains uncharacterized. Here we show that ALDH1A1–posi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Sgobio, Carmelo, Wu, Junbing, Zheng, Wang, Chen, Xi, Pan, Jing, Salinas, Armando G., Davis, Margaret I., Lovinger, David M., Cai, Huaibin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509666/
https://ncbi.nlm.nih.gov/pubmed/28706191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05598-1
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