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Aldehyde dehydrogenase 1–positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum

Aldehyde dehydrogenase 1 (ALDH1A1)–positive dopaminergic (DA) neurons at the ventral substantia nigra pars compacta (SNpc) preferentially degenerate in Parkinson’s disease (PD). Their projection pattern and dopamine release properties, however, remains uncharacterized. Here we show that ALDH1A1–posi...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Sgobio, Carmelo, Wu, Junbing, Zheng, Wang, Chen, Xi, Pan, Jing, Salinas, Armando G., Davis, Margaret I., Lovinger, David M., Cai, Huaibin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509666/
https://ncbi.nlm.nih.gov/pubmed/28706191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05598-1
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