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Aldehyde Dehydrogenase 1 making molecular inroads into the differential vulnerability of nigrostriatal dopaminergic neuron subtypes in Parkinson’s disease

A preferential dysfunction/loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) accounts for the main motor symptoms of Parkinson’s disease (PD), the most common degenerative movement disorder. However, the neuronal loss is not stochastic, but rather displays regionally sel...

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Detalhes bibliográficos
Publicado no:Transl Neurodegener
Main Authors: Cai, Huaibin, Liu, Guoxiang, Sun, Lixin, Ding, Jinhui
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334846/
https://ncbi.nlm.nih.gov/pubmed/25705376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-9158-3-27
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