Aldehyde Dehydrogenase 1 making molecular inroads into the differential vulnerability of nigrostriatal dopaminergic neuron subtypes in Parkinson’s disease

A preferential dysfunction/loss of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc) accounts for the main motor symptoms of Parkinson’s disease (PD), the most common degenerative movement disorder. However, the neuronal loss is not stochastic, but rather displays regionally sel...

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Vydáno v:Transl Neurodegener
Hlavní autoři: Cai, Huaibin, Liu, Guoxiang, Sun, Lixin, Ding, Jinhui
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Review
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4334846/
https://ncbi.nlm.nih.gov/pubmed/25705376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2047-9158-3-27
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