Rebalance of Striatal NMDA/AMPA Receptor Ratio Underlies the Reduced Emergence of Dyskinesia During D2-Like Dopamine Agonist Treatment in Experimental Parkinson's Disease

Dopamine replacement with levodopa (l-DOPA) represents the mainstay of Parkinson's disease (PD) therapy. Nevertheless, this well established therapeutic intervention loses efficacy with the progression of the disease and patients develop invalidating side effects, known in their complex as l-DO...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Bagetta, Vincenza, Sgobio, Carmelo, Pendolino, Valentina, Del Papa, Giulia, Tozzi, Alessandro, Ghiglieri, Veronica, Giampà, Carmela, Zianni, Elisa, Gardoni, Fabrizio, Calabresi, Paolo, Picconi, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621675/
https://ncbi.nlm.nih.gov/pubmed/23223310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2664-12.2012
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