Rebalance of Striatal NMDA/AMPA Receptor Ratio Underlies the Reduced Emergence of Dyskinesia During D2-Like Dopamine Agonist Treatment in Experimental Parkinson's Disease

Dopamine replacement with levodopa (l-DOPA) represents the mainstay of Parkinson's disease (PD) therapy. Nevertheless, this well established therapeutic intervention loses efficacy with the progression of the disease and patients develop invalidating side effects, known in their complex as l-DO...

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Udgivet i:J Neurosci
Main Authors: Bagetta, Vincenza, Sgobio, Carmelo, Pendolino, Valentina, Del Papa, Giulia, Tozzi, Alessandro, Ghiglieri, Veronica, Giampà, Carmela, Zianni, Elisa, Gardoni, Fabrizio, Calabresi, Paolo, Picconi, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2012
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6621675/
https://ncbi.nlm.nih.gov/pubmed/23223310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2664-12.2012
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