Distinct Levels of Dopamine Denervation Differentially Alter Striatal Synaptic Plasticity and NMDA Receptor Subunit Composition

A correct interplay between dopamine (DA) and glutamate is essential for corticostriatal synaptic plasticity and motor activity. In an experimental model of Parkinson's disease (PD) obtained in rats, the complete depletion of striatal DA, mimicking advanced stages of the disease, results in the...

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Published in:J Neurosci
Main Authors: Paillé, Vincent, Picconi, Barbara, Bagetta, Vincenza, Ghiglieri, Veronica, Sgobio, Carmelo, Di Filippo, Massimiliano, Viscomi, Maria T., Giampà, Carmela, Fusco, Francesca R., Gardoni, Fabrizio, Bernardi, Giorgio, Greengard, Paul, Di Luca, Monica, Calabresi, Paolo
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6634757/
https://ncbi.nlm.nih.gov/pubmed/20962239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2149-10.2010
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