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Region-specific restoration of striatal synaptic plasticity by dopamine grafts in experimental parkinsonism

Intrastriatal transplantation of dopaminergic neurons can restore striatal dopamine levels and improve parkinsonian deficits, but the mechanisms underlying these effects are poorly understood. Here, we show that transplants of dopamine neurons partially restore activity-dependent synaptic plasticity...

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Главные авторы: Rylander, Daniella, Bagetta, Vincenza, Pendolino, Valentina, Zianni, Elisa, Grealish, Shane, Gardoni, Fabrizio, Di Luca, Monica, Calabresi, Paolo, Cenci, M. Angela, Picconi, Barbara
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831970/
https://ncbi.nlm.nih.gov/pubmed/24170862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311187110
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