Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice

di Sgobio, Carmelo, Sun, Lixin, Ding, Jinhui, Herms, Jochen, Lovinger, David M., Cai, Huaibin
Pubblicato in Sci Rep (2019)

Optogenetic Measurement of Presynaptic Calcium Transients Using Conditional Genetically Encoded Calcium Indicator Expression in Dopaminergic Neurons

di Sgobio, Carmelo, Kupferschmidt, David A., Cui, Guohong, Sun, Lixin, Li, Zheng, Cai, Huaibin, Lovinger, David M.
Pubblicazione 2014

Enriched environment promotes behavioral and morphological recovery in a mouse model for the fragile X syndrome

di Restivo, Leonardo, Ferrari, Francesca, Passino, Enrica, Sgobio, Carmelo, Bock, Jörg, Oostra, Ben A., Bagni, Claudia, Ammassari-Teule, Martine
Pubblicazione 2005

Dopamine-Dependent Long-Term Depression Is Expressed in Striatal Spiny Neurons of Both Direct and Indirect Pathways: Implications for Parkinson's Disease

di Bagetta, Vincenza, Picconi, Barbara, Marinucci, Silvia, Sgobio, Carmelo, Pendolino, Valentina, Ghiglieri, Veronica, Fusco, Francesca R., Giampà, Carmen, Calabresi, Paolo
Pubblicato in J Neurosci (2011)

Tau deletion reduces plaque‐associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease

di Peters, Finn, Salihoglu, Hazal, Pratsch, Katrin, Herzog, Etienne, Pigoni, Martina, Sgobio, Carmelo, Lichtenthaler, Stefan F, Neumann, Ulf, Herms, Jochen
Pubblicato in EMBO J (2019)

Aldehyde dehydrogenase 1–positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum

di Sgobio, Carmelo, Wu, Junbing, Zheng, Wang, Chen, Xi, Pan, Jing, Salinas, Armando G., Davis, Margaret I., Lovinger, David M., Cai, Huaibin
Pubblicato in Sci Rep (2017)

No apparent transmission of transgenic α–synuclein into nigrostriatal dopaminergic neurons in multiple mouse models

di Sastry, Namratha, Zheng, Wang, Liu, Guoxiang, Wang, Helen, Chen, Xi, Cai, Michael, Contractor, Parth, Sgobio, Carmelo, Sun, Lixin, Xie, Chengsong, Cai, Huaibin
Pubblicato in Transl Neurodegener (2015)

Rebalance of Striatal NMDA/AMPA Receptor Ratio Underlies the Reduced Emergence of Dyskinesia During D2-Like Dopamine Agonist Treatment in Experimental Parkinson's Disease

di Bagetta, Vincenza, Sgobio, Carmelo, Pendolino, Valentina, Del Papa, Giulia, Tozzi, Alessandro, Ghiglieri, Veronica, Giampà, Carmela, Zianni, Elisa, Gardoni, Fabrizio, Calabresi, Paolo, Picconi, Barbara
Pubblicato in J Neurosci (2012)

LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

di Parisiadou, Loukia, Yu, Jia, Sgobio, Carmelo, Xie, Chengsong, Liu, Guoxiang, Sun, Lixin, Gu, Xing-Long, Lin, Xian, Crowley, Nicole A., Lovinger, David, Cai, Huaibin
Pubblicazione 2014

Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D‐serine homeostasis

di Zou, Chengyu, Crux, Sophie, Marinesco, Stephane, Montagna, Elena, Sgobio, Carmelo, Shi, Yuan, Shi, Song, Zhu, Kaichuan, Dorostkar, Mario M, Müller, Ulrike C, Herms, Jochen
Pubblicato in EMBO J (2016)

TrkB/BDNF-Dependent Striatal Plasticity and Behavior in a Genetic Model of Epilepsy: Modulation by Valproic Acid

di Ghiglieri, Veronica, Sgobio, Carmelo, Patassini, Stefano, Bagetta, Vincenza, Fejtova, Anna, Giampà, Carmela, Marinucci, Silvia, Heyden, Alexandra, Gundelfinger, Eckart D, Fusco, Francesca R, Calabresi, Paolo, Picconi, Barbara
Pubblicazione 2010

α-Synuclein Mutation Inhibits Endocytosis at Mammalian Central Nerve Terminals

di Xu, Jianhua, Wu, Xin-Sheng, Sheng, Jiansong, Zhang, Zhen, Yue, Hai-Yuan, Sun, Lixin, Sgobio, Carmelo, Lin, Xian, Peng, Shiyong, Jin, Yinghui, Gan, Lin, Cai, Huaibin, Wu, Ling-Gang
Pubblicato in J Neurosci (2016)

Distinct Levels of Dopamine Denervation Differentially Alter Striatal Synaptic Plasticity and NMDA Receptor Subunit Composition

di Paillé, Vincent, Picconi, Barbara, Bagetta, Vincenza, Ghiglieri, Veronica, Sgobio, Carmelo, Di Filippo, Massimiliano, Viscomi, Maria T., Giampà, Carmela, Fusco, Francesca R., Gardoni, Fabrizio, Bernardi, Giorgio, Greengard, Paul, Di Luca, Monica, Calabresi, Paolo
Pubblicato in J Neurosci (2010)

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic...

di Liu, Guoxiang, Sgobio, Carmelo, Gu, Xinglong, Sun, Lixin, Lin, Xian, Yu, Jia, Parisiadou, Loukia, Xie, Chengsong, Sastry, Namratha, Ding, Jinhui, Lohr, Kelly M., Miller, Gary W., Mateo, Yolanda, Lovinger, David M., Cai, Huaibin
Pubblicato in Hum Mol Genet (2015)

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease

di Dunn, Amy R., Stout, Kristen A., Ozawa, Minagi, Lohr, Kelly M., Hoffman, Carlie A., Bernstein, Alison I., Li, Yingjie, Wang, Minzheng, Sgobio, Carmelo, Sastry, Namratha, Cai, Huaibin, Caudle, W. Michael, Miller, Gary W.
Pubblicato in Proc Natl Acad Sci U S A (2017)

Conditional Expression of Parkinson's Disease-Related Mutant α-Synuclein in the Midbrain Dopaminergic Neurons Causes Progressive Neurodegeneration and Degradation of Transcription...

di Lin, Xian, Parisiadou, Loukia, Sgobio, Carmelo, Liu, Guoxiang, Yu, Jia, Sun, Lixin, Shim, Hoon, Gu, Xing-Long, Luo, Jing, Long, Cai-Xia, Ding, Jinhui, Mateo, Yolanda, Sullivan, Patricia H., Wu, Ling-Gang, Goldstein, David S., Lovinger, David, Cai, Huaibin
Pubblicazione 2012

Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second-Generation Amyloid-β Mouse Model

di Sacher, Christian, Blume, Tanja, Beyer, Leonie, Peters, Finn, Eckenweber, Florian, Sgobio, Carmelo, Deussing, Maximilian, Albert, Nathalie L., Unterrainer, Marcus, Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Brzak, Irena, Neumann, Ulf, Saito, Takashi, Saido, Takaomi C., Bartenstein, Peter, Rominger, Axel, Herms, Jochen, Brendel, Matthias
Pubblicato in J Nucl Med (2019)