Unbalanced calcium channel activity underlies selective vulnerability of nigrostriatal dopaminergic terminals in Parkinsonian mice

gan Sgobio, Carmelo, Sun, Lixin, Ding, Jinhui, Herms, Jochen, Lovinger, David M., Cai, Huaibin
Cyhoeddwyd yn Sci Rep (2019)

Optogenetic Measurement of Presynaptic Calcium Transients Using Conditional Genetically Encoded Calcium Indicator Expression in Dopaminergic Neurons

gan Sgobio, Carmelo, Kupferschmidt, David A., Cui, Guohong, Sun, Lixin, Li, Zheng, Cai, Huaibin, Lovinger, David M.
Cyhoeddwyd 2014

Enriched environment promotes behavioral and morphological recovery in a mouse model for the fragile X syndrome

gan Restivo, Leonardo, Ferrari, Francesca, Passino, Enrica, Sgobio, Carmelo, Bock, Jörg, Oostra, Ben A., Bagni, Claudia, Ammassari-Teule, Martine
Cyhoeddwyd 2005

Dopamine-Dependent Long-Term Depression Is Expressed in Striatal Spiny Neurons of Both Direct and Indirect Pathways: Implications for Parkinson's Disease

gan Bagetta, Vincenza, Picconi, Barbara, Marinucci, Silvia, Sgobio, Carmelo, Pendolino, Valentina, Ghiglieri, Veronica, Fusco, Francesca R., Giampà, Carmen, Calabresi, Paolo
Cyhoeddwyd yn J Neurosci (2011)

Tau deletion reduces plaque‐associated BACE1 accumulation and decelerates plaque formation in a mouse model of Alzheimer's disease

gan Peters, Finn, Salihoglu, Hazal, Pratsch, Katrin, Herzog, Etienne, Pigoni, Martina, Sgobio, Carmelo, Lichtenthaler, Stefan F, Neumann, Ulf, Herms, Jochen
Cyhoeddwyd yn EMBO J (2019)

Aldehyde dehydrogenase 1–positive nigrostriatal dopaminergic fibers exhibit distinct projection pattern and dopamine release dynamics at mouse dorsal striatum

gan Sgobio, Carmelo, Wu, Junbing, Zheng, Wang, Chen, Xi, Pan, Jing, Salinas, Armando G., Davis, Margaret I., Lovinger, David M., Cai, Huaibin
Cyhoeddwyd yn Sci Rep (2017)

No apparent transmission of transgenic α–synuclein into nigrostriatal dopaminergic neurons in multiple mouse models

gan Sastry, Namratha, Zheng, Wang, Liu, Guoxiang, Wang, Helen, Chen, Xi, Cai, Michael, Contractor, Parth, Sgobio, Carmelo, Sun, Lixin, Xie, Chengsong, Cai, Huaibin
Cyhoeddwyd yn Transl Neurodegener (2015)

Rebalance of Striatal NMDA/AMPA Receptor Ratio Underlies the Reduced Emergence of Dyskinesia During D2-Like Dopamine Agonist Treatment in Experimental Parkinson's Disease

gan Bagetta, Vincenza, Sgobio, Carmelo, Pendolino, Valentina, Del Papa, Giulia, Tozzi, Alessandro, Ghiglieri, Veronica, Giampà, Carmela, Zianni, Elisa, Gardoni, Fabrizio, Calabresi, Paolo, Picconi, Barbara
Cyhoeddwyd yn J Neurosci (2012)

LRRK2 regulates synaptogenesis and dopamine receptor activation through modulation of PKA activity

gan Parisiadou, Loukia, Yu, Jia, Sgobio, Carmelo, Xie, Chengsong, Liu, Guoxiang, Sun, Lixin, Gu, Xing-Long, Lin, Xian, Crowley, Nicole A., Lovinger, David, Cai, Huaibin
Cyhoeddwyd 2014

Amyloid precursor protein maintains constitutive and adaptive plasticity of dendritic spines in adult brain by regulating D‐serine homeostasis

gan Zou, Chengyu, Crux, Sophie, Marinesco, Stephane, Montagna, Elena, Sgobio, Carmelo, Shi, Yuan, Shi, Song, Zhu, Kaichuan, Dorostkar, Mario M, Müller, Ulrike C, Herms, Jochen
Cyhoeddwyd yn EMBO J (2016)

TrkB/BDNF-Dependent Striatal Plasticity and Behavior in a Genetic Model of Epilepsy: Modulation by Valproic Acid

gan Ghiglieri, Veronica, Sgobio, Carmelo, Patassini, Stefano, Bagetta, Vincenza, Fejtova, Anna, Giampà, Carmela, Marinucci, Silvia, Heyden, Alexandra, Gundelfinger, Eckart D, Fusco, Francesca R, Calabresi, Paolo, Picconi, Barbara
Cyhoeddwyd 2010

α-Synuclein Mutation Inhibits Endocytosis at Mammalian Central Nerve Terminals

gan Xu, Jianhua, Wu, Xin-Sheng, Sheng, Jiansong, Zhang, Zhen, Yue, Hai-Yuan, Sun, Lixin, Sgobio, Carmelo, Lin, Xian, Peng, Shiyong, Jin, Yinghui, Gan, Lin, Cai, Huaibin, Wu, Ling-Gang
Cyhoeddwyd yn J Neurosci (2016)

Distinct Levels of Dopamine Denervation Differentially Alter Striatal Synaptic Plasticity and NMDA Receptor Subunit Composition

gan Paillé, Vincent, Picconi, Barbara, Bagetta, Vincenza, Ghiglieri, Veronica, Sgobio, Carmelo, Di Filippo, Massimiliano, Viscomi, Maria T., Giampà, Carmela, Fusco, Francesca R., Gardoni, Fabrizio, Bernardi, Giorgio, Greengard, Paul, Di Luca, Monica, Calabresi, Paolo
Cyhoeddwyd yn J Neurosci (2010)

Selective expression of Parkinson's disease-related Leucine-rich repeat kinase 2 G2019S missense mutation in midbrain dopaminergic neurons impairs dopamine release and dopaminergic...

gan Liu, Guoxiang, Sgobio, Carmelo, Gu, Xinglong, Sun, Lixin, Lin, Xian, Yu, Jia, Parisiadou, Loukia, Xie, Chengsong, Sastry, Namratha, Ding, Jinhui, Lohr, Kelly M., Miller, Gary W., Mateo, Yolanda, Lovinger, David M., Cai, Huaibin
Cyhoeddwyd yn Hum Mol Genet (2015)

Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease

gan Dunn, Amy R., Stout, Kristen A., Ozawa, Minagi, Lohr, Kelly M., Hoffman, Carlie A., Bernstein, Alison I., Li, Yingjie, Wang, Minzheng, Sgobio, Carmelo, Sastry, Namratha, Cai, Huaibin, Caudle, W. Michael, Miller, Gary W.
Cyhoeddwyd yn Proc Natl Acad Sci U S A (2017)

Conditional Expression of Parkinson's Disease-Related Mutant α-Synuclein in the Midbrain Dopaminergic Neurons Causes Progressive Neurodegeneration and Degradation of Transcription...

gan Lin, Xian, Parisiadou, Loukia, Sgobio, Carmelo, Liu, Guoxiang, Yu, Jia, Sun, Lixin, Shim, Hoon, Gu, Xing-Long, Luo, Jing, Long, Cai-Xia, Ding, Jinhui, Mateo, Yolanda, Sullivan, Patricia H., Wu, Ling-Gang, Goldstein, David S., Lovinger, David, Cai, Huaibin
Cyhoeddwyd 2012

Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second-Generation Amyloid-β Mouse Model

gan Sacher, Christian, Blume, Tanja, Beyer, Leonie, Peters, Finn, Eckenweber, Florian, Sgobio, Carmelo, Deussing, Maximilian, Albert, Nathalie L., Unterrainer, Marcus, Lindner, Simon, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Brzak, Irena, Neumann, Ulf, Saito, Takashi, Saido, Takaomi C., Bartenstein, Peter, Rominger, Axel, Herms, Jochen, Brendel, Matthias
Cyhoeddwyd yn J Nucl Med (2019)