Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells

Por Kang, Jian, Sergio, C Marcelo, Sutherland, Robert L, Musgrove, Elizabeth A
Publicado em 2014

Differences in degradation lead to asynchronous expression of cyclin E1 and cyclin E2 in cancer cells

Por Caldon, C. Elizabeth, Sergio, C. Marcelo, Sutherland, Robert L., Musgrove, Elizabeth A.
Publicado em 2013

Cyclin E2 induces genomic instability by mechanisms distinct from cyclin E1

Por Caldon, C. Elizabeth, Sergio, C. Marcelo, Burgess, Andrew, Deans, Andrew J., Sutherland, Robert L., Musgrove, Elizabeth A.
Publicado em 2013

Estrogen Regulation of Cyclin E2 Requires Cyclin D1 but Not c-Myc

Por Caldon, C. Elizabeth, Sergio, C. Marcelo, Schütte, Judith, Boersma, Marijke N., Sutherland, Robert L., Carroll, Jason S., Musgrove, Elizabeth A.
Publicado em 2009

The estrogen and c-Myc target gene HSPC111 is over-expressed in breast cancer and associated with poor patient outcome

Por Butt, Alison J, Sergio, C Marcelo, Inman, Claire K, Anderson, Luke R, McNeil, Catriona M, Russell, Amanda J, Nousch, Marco, Preiss, Thomas, Biankin, Andrew V, Sutherland, Robert L, Musgrove, Elizabeth A
Publicado em 2008

Identification of Functional Networks of Estrogen- and c-Myc-Responsive Genes and Their Relationship to Response to Tamoxifen Therapy in Breast Cancer

Por Musgrove, Elizabeth A., Sergio, C. Marcelo, Loi, Sherene, Inman, Claire K., Anderson, Luke R., Alles, M. Chehani, Pinese, Mark, Caldon, C. Elizabeth, Schütte, Judith, Gardiner-Garden, Margaret, Ormandy, Christopher J., McArthur, Grant, Butt, Alison J., Sutherland, Robert L.
Publicado em 2008

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells

Por Gallego-Ortega, David, Ledger, Anita, Roden, Daniel L., Law, Andrew M. K., Magenau, Astrid, Kikhtyak, Zoya, Cho, Christina, Allerdice, Stephanie L., Lee, Heather J., Valdes-Mora, Fatima, Herrmann, David, Salomon, Robert, Young, Adelaide I. J., Lee, Brian Y., Sergio, C. Marcelo, Kaplan, Warren, Piggin, Catherine, Conway, James R. W., Rabinovich, Brian, Millar, Ewan K. A., Oakes, Samantha R., Chtanova, Tatyana, Swarbrick, Alexander, Naylor, Matthew J., O’Toole, Sandra, Green, Andrew R., Timpson, Paul, Gee, Julia M. W., Ellis, Ian O., Clark, Susan J., Ormandy, Christopher J.
Publicado no PLoS Biol (2015)