Reprogramming the Methylome: Erasing Memory and Creating Diversity

Por Lee, Heather J., Hore, Timothy A., Reik, Wolf
Publicado em 2014

DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

Por Angermueller, Christof, Lee, Heather J., Reik, Wolf, Stegle, Oliver
Publicado no Genome Biol (2017)

Erratum to: DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning

Por Angermueller, Christof, Lee, Heather J., Reik, Wolf, Stegle, Oliver
Publicado no Genome Biol (2017)

Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity

Por Clark, Stephen J., Lee, Heather J., Smallwood, Sébastien A., Kelsey, Gavin, Reik, Wolf
Publicado no Genome Biol (2016)

Etoposide Induces Nuclear Re-Localisation of AID

Por Lambert, Laurens J., Walker, Simon, Feltham, Jack, Lee, Heather J., Reik, Wolf, Houseley, Jonathan
Publicado em 2013

ELF5 isoform expression is tissue-specific and significantly altered in cancer

Por Piggin, Catherine L., Roden, Daniel L., Gallego-Ortega, David, Lee, Heather J., Oakes, Samantha R., Ormandy, Christopher J.
Publicado no Breast Cancer Res (2016)

Allosteric activation of the extracellular Ca(2+)-sensing receptor by L-amino acids enhances ERK1/2 phosphorylation

Por Lee, Heather J., Mun, Hee-Chang, Lewis, Narelle C., Crouch, Michael F., Culverston, Emma L., Mason, Rebecca S., Conigrave, Arthur D.
Publicado em 2007

Single-Cell Genome-Wide Bisulfite Sequencing for Assessing Epigenetic Heterogeneity

Por Smallwood, Sébastien A, Lee, Heather J, Angermueller, Christof, Krueger, Felix, Saadeh, Heba, Peat, Julian, Andrews, Simon R, Stegle, Oliver, Reik, Wolf, Kelsey, Gavin
Publicado em 2014

Tracking the embryonic stem cell transition from ground state pluripotency

Por Kalkan, Tüzer, Olova, Nelly, Roode, Mila, Mulas, Carla, Lee, Heather J., Nett, Isabelle, Marks, Hendrik, Walker, Rachael, Stunnenberg, Hendrik G., Lilley, Kathryn S., Nichols, Jennifer, Reik, Wolf, Bertone, Paul, Smith, Austin
Publicado no Development (2017)

Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity

Por Angermueller, Christof, Clark, Stephen J., Lee, Heather J., Macaulay, Iain C., Teng, Mabel J., Hu, Tim Xiaoming, Krueger, Felix, Smallwood, Sebastien, Ponting, Chris P., Voet, Thierry, Kelsey, Gavin, Stegle, Oliver, Reik, Wolf
Publicado no Nat Methods (2016)

FGF signalling inhibition in ESCs drives rapid genome-wide demethylation to the epigenetic ground state of pluripotency

Por Ficz, Gabriella, Hore, Timothy A, Santos, Fatima, Lee, Heather J, Dean, Wendy, Arand, Julia, Krueger, Felix, Oxley, David, Paul, Yu-Lee, Walter, Jörn, Cook, Simon J, Andrews, Simon, Branco, Miguel R, Reik, Wolf
Publicado em 2013

FGF Signaling Inhibition in ESCs Drives Rapid Genome-wide Demethylation to the Epigenetic Ground State of Pluripotency

Por Ficz, Gabriella, Hore, Timothy A., Santos, Fátima, Lee, Heather J., Dean, Wendy, Arand, Julia, Krueger, Felix, Oxley, David, Paul, Yu-Lee, Walter, Jörn, Cook, Simon J., Andrews, Simon, Branco, Miguel R., Reik, Wolf
Publicado em 2013

Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer

Por Schramek, Daniel, Leibbrandt, Andreas, Sigl, Verena, Kenner, Lukas, Pospisilik, John A., Lee, Heather J., Hanada, Reiko, Joshi, Purna A., Aliprantis, Antonios, Glimcher, Laurie, Pasparakis, Manolis, Khokha, Rama, Ormandy, Christopher J., Widschwendter, Martin, Schett, Georg, Penninger, Josef M.
Publicado em 2010

ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer

Por Kalyuga, Maria, Gallego-Ortega, David, Lee, Heather J., Roden, Daniel L., Cowley, Mark J., Caldon, C. Elizabeth, Stone, Andrew, Allerdice, Stephanie L., Valdes-Mora, Fatima, Launchbury, Rosalind, Statham, Aaron L., Armstrong, Nicola, Alles, M. Chehani, Young, Adelaide, Egger, Andrea, Au, Wendy, Piggin, Catherine L., Evans, Cara J., Ledger, Anita, Brummer, Tilman, Oakes, Samantha R., Kaplan, Warren, Gee, Julia M. W., Nicholson, Robert I., Sutherland, Robert L., Swarbrick, Alexander, Naylor, Matthew J., Clark, Susan J., Carroll, Jason S., Ormandy, Christopher J.
Publicado em 2012

ELF5 Drives Lung Metastasis in Luminal Breast Cancer through Recruitment of Gr1+ CD11b+ Myeloid-Derived Suppressor Cells

Por Gallego-Ortega, David, Ledger, Anita, Roden, Daniel L., Law, Andrew M. K., Magenau, Astrid, Kikhtyak, Zoya, Cho, Christina, Allerdice, Stephanie L., Lee, Heather J., Valdes-Mora, Fatima, Herrmann, David, Salomon, Robert, Young, Adelaide I. J., Lee, Brian Y., Sergio, C. Marcelo, Kaplan, Warren, Piggin, Catherine, Conway, James R. W., Rabinovich, Brian, Millar, Ewan K. A., Oakes, Samantha R., Chtanova, Tatyana, Swarbrick, Alexander, Naylor, Matthew J., O’Toole, Sandra, Green, Andrew R., Timpson, Paul, Gee, Julia M. W., Ellis, Ian O., Clark, Susan J., Ormandy, Christopher J.
Publicado no PLoS Biol (2015)