ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer

We have previously shown that during pregnancy the E-twenty-six (ETS) transcription factor ELF5 directs the differentiation of mammary progenitor cells toward the estrogen receptor (ER)-negative and milk producing cell lineage, raising the possibility that ELF5 may suppress the estrogen sensitivity...

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Detalhes bibliográficos
Main Authors: Kalyuga, Maria, Gallego-Ortega, David, Lee, Heather J., Roden, Daniel L., Cowley, Mark J., Caldon, C. Elizabeth, Stone, Andrew, Allerdice, Stephanie L., Valdes-Mora, Fatima, Launchbury, Rosalind, Statham, Aaron L., Armstrong, Nicola, Alles, M. Chehani, Young, Adelaide, Egger, Andrea, Au, Wendy, Piggin, Catherine L., Evans, Cara J., Ledger, Anita, Brummer, Tilman, Oakes, Samantha R., Kaplan, Warren, Gee, Julia M. W., Nicholson, Robert I., Sutherland, Robert L., Swarbrick, Alexander, Naylor, Matthew J., Clark, Susan J., Carroll, Jason S., Ormandy, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3531499/
https://ncbi.nlm.nih.gov/pubmed/23300383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001461
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