ELF5 modulates the estrogen receptor cistrome in breast cancer

Acquired resistance to endocrine therapy is responsible for half of the therapeutic failures in the treatment of breast cancer. Recent findings have implicated increased expression of the ETS transcription factor ELF5 as a potential modulator of estrogen action and driver of endocrine resistance, an...

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Vydáno v:PLoS Genet
Hlavní autoři: Piggin, Catherine L., Roden, Daniel L., Law, Andrew M. K., Molloy, Mark P., Krisp, Christoph, Swarbrick, Alexander, Naylor, Matthew J., Kalyuga, Maria, Kaplan, Warren, Oakes, Samantha R., Gallego-Ortega, David, Clark, Susan J., Carroll, Jason S., Bartonicek, Nenad, Ormandy, Christopher J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2020
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959601/
https://ncbi.nlm.nih.gov/pubmed/31895944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008531
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