ELF5 modulates the estrogen receptor cistrome in breast cancer

Acquired resistance to endocrine therapy is responsible for half of the therapeutic failures in the treatment of breast cancer. Recent findings have implicated increased expression of the ETS transcription factor ELF5 as a potential modulator of estrogen action and driver of endocrine resistance, an...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Piggin, Catherine L., Roden, Daniel L., Law, Andrew M. K., Molloy, Mark P., Krisp, Christoph, Swarbrick, Alexander, Naylor, Matthew J., Kalyuga, Maria, Kaplan, Warren, Oakes, Samantha R., Gallego-Ortega, David, Clark, Susan J., Carroll, Jason S., Bartonicek, Nenad, Ormandy, Christopher J.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2020
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6959601/
https://ncbi.nlm.nih.gov/pubmed/31895944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008531
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